H18.5 H18.1
Conditions
Interventions
> 18 years of age
phakic or pseudophakic
Group 1: male or female
diagnosis of Fuchs endothelial dystrophy or corneal endothelial failure - indication for DMEK (Descemet Membrane Endothelial Keratoplasty)
Diagnostic procedures:
• General medical history
• BCVA (Bes
diagnosis of corneal diseases or scars - indication for penetrating keratoplasty
Diagnostic procedures:
• General medical history
• BCVA
• Slit lamp examination
• Intraocular pressure measuerement
•
Sponsors
Universitätsmedizin der Johannes Gutenberg-Universität Mainz
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: DMEK group: male or female; > 18 years of age; phakic or pseudophakic; diagnosis of Fuchs endothelial dystrophy or corneal endothelial failure - indication for DMEK PKP group: male or female; > 18 years of age; phakic or pseudophakic; diagnosis of corneal diseases or scars - indication for penetrating keratoplasty
Exclusion criteria
Exclusion criteria: History of penetrating or lamellar keratoplasty; indication for HLA-typed keratoplasty; patient not able to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Best corrected visual acuity 12 months after keratoplasty | — |
Secondary
| Measure | Time frame |
|---|---|
| Endothelial cell count 12 months after keratoplasty | — |
Countries
Germany
Contacts
Public ContactJoanna Wasielica-Poslednik
Augenklinik und Poliklinik der Universitätsmedizin Mainz
Outcome results
None listed