The use of Perisolv® and hyaluronic acid during scaling and root planing

The use of Perisolv® and hyaluronic acid during scaling and root planing - perisolv

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00017415

Enrollment

Registered

2019-06-03

Start date

2019-05-20

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K05.3

Interventions

Group 1: Test group: scaling and root planing with instillation of perisolv for 30 seconds, after that instillation of hyadent. Group 2: Control group: scaling and root planing with hand- and ultrason

Eligibility

Sex/Gender

All

Age

40 Years to 65 Years

Inclusion criteria

Inclusion criteria: - chronic Periodontitis, after active phase of the treatment of periodontitis - minimum 16 natural teeth - age between 40 and 65 years - 2 – 8 sites with probing depth = 5 mm, 5 mm + BOP (Bleeding on Probing) positive, 4 mm + BOP positive, not at adjacent teeth, 6 mm at monoradicular teeth at the appointment of reevaluation of SRP (Scaling und Rootplanning), after active Phase of periodontal treatment or during supportive periodontal therapy

Exclusion criteria

Exclusion criteria: - patients younger than 18 years - Periodontitis in relation with systemic diseases - intake of immunosuppressive or immunomodulating drugs - intake of antibiotics within the last 3 months befoe the study - gravidity or lactation - cancer - Smoking of more than 5 cigarettes per day - allergy in relation to ingredients of the used products - Special nutrition (e. g. vegane nutrition)

Design outcomes

Primary

Measure	Time frame
Improvement of probing depth, determined via manual periodontal probe at baseline as well as after three and six months.	—

Secondary

Measure	Time frame
Improvement of attachment Level, bleeding on probing as well as of microbiological and biochemical variables Clinical variables are determined using a manual periodontal probe at baseline as well as after three and six months. Attachment level and bleeding on probing are measured with manual periodontal probe. Microbiological and biochemical variables are determined using PCR-kits at the same time points.	—

Measure

Time frame

Improvement of attachment Level, bleeding on probing as well as of microbiological and biochemical variables Clinical variables are determined using a manual periodontal probe at baseline as well as after three and six months. Attachment level and bleeding on probing are measured with manual periodontal probe. Microbiological and biochemical variables are determined using PCR-kits at the same time points.

—

Countries

Germany

Contacts

Public ContactHolger Jentsch

Universität Leipzig, FB Parodontologie der Poliklinik für Zahnerhaltung und Parodontologie

jenh@medizin.uni-leipzig.de0341-9721208

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: May 31, 2026