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Indications and Safety Profile of Musculoskeletal Contrast-Enhanced Ultrasound with SonoVue®

Indications and Safety Profile of Musculoskeletal Contrast-Enhanced Ultrasound with SonoVue®

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00017406
Enrollment
700
Registered
2019-06-14
Start date
2017-08-16
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

PSEUDARTHROSIS SUPRASPINATUS TENDON RUPTURE

Interventions

Group 1: This study gives an overview of current musculoskeletal CEUS (contrast-enhanced ultrasound) applications and investigated the incidence of adverse events (AEs) in this particular cohort.

Sponsors

Zentrum für Orthopädie, Unfallchirurgie und Paraplegiologie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Data of study patients, who underwent musculoskeletal CEUS examinations with SonoVue® between 2012 and 2019, were included.

Exclusion criteria

Exclusion criteria: Exclusion criteria for the utilization of CEUS were a history of recent myocardial infarction, an intracardial right-left shunt, uncontrollable fluctuations of blood pressure, severe respiratory disease (pulmonary arterial hypertension (PAH), severe acute respiratory syndrome (SARS), during pregnancy and while breast-feeding (missing studies, no evidence) or any known allergic reaction to SonoVue® as well as other similar contrast agents. Further exclusion criteria were an age younger than 18 years and the lack of the patients’ informed consent.

Design outcomes

Primary

MeasureTime frame
Incidence of adverse Events of every application of SonoVue®

Secondary

MeasureTime frame
Incidence of severe adverse Events of every application of SonoVue®

Countries

Germany

Contacts

Public ContactJulian Doll

Zentrum für Orthopädie, Unfallchirurgie und Paraplegiologie

julian.doll@med.uni-heidelberg.de062215636388

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026