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Breakdown, Identification and Observation of the microenvironment of acute and chronic wounds

Breakdown, Identification and Observation of the microenvironment of acute and chronic wounds - Wound-BIOME

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00017390
Enrollment
160
Registered
2019-07-10
Start date
2018-04-18
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute wounds chronic wounds

Interventions

Group 1: Acute, non-infected wounds (control group
observative, non-interventionell) As part of the regular medical wound treatment, sterile wound swabs are obtained from the wound bed of open acute and chronic wounds for biomaterial acquisition. Su

Sponsors

Institut für Translationale Wundforschung, Zentrum für biomedizinische Ausbildung und Forschung (ZBAF), Universität Witten/Herdecke
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Men and women, aged 18 years or older 2. Signed informed consent 3. Existing wound for longer than 8 weeks ('chronic') OR 4. Existing wound for over 24 hours and less than 6 days after traumatic event or surgical intervention ('acute')

Exclusion criteria

Exclusion criteria: 1. Dry necrosis, dry wound bed, no wound bed sampling possible 2. Aged < 18 years 3. Pregnancy or nursing period 4. Wound of malignant entity (e.g. exulcerating tumor) 5. Non written consent

Design outcomes

Primary

MeasureTime frame
Goal criterion: Acquisition of biological material for biomolecular analysis of chronic wound entities compared to acute wounds for correlation with healing phase and progression. Sampling endpoint is marked by complete wound closure/epithelization making further wound bed swabbing impossible.

Countries

Germany

Contacts

Public ContactJulian-Dario Rembe

Institut für Translationale Wundforschung, Zentrum für biomedizinische Ausbildung und Forschung (ZBAF), Universität Witten/Herdecke

julian-dario.rembe@uni-wh.de+491626368722

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026