Thromboelastometry Guided Blood-Component Therapy After Cardiac Surgery: A Randomized Study

Thromboelastometry Guided Blood-Component Therapy After Cardiac Surgery: A Randomized Study - TEG-Guide

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00017367

Enrollment

200

Registered

2019-06-18

Start date

2007-03-15

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

T81.0 D68.4

Interventions

Group 1: Thrombelastometry-guided blood-component transfusion protocol (4-chamber ROTEM™) Group 2: Standard-coagulation-testing-based transfusion protocol (Control)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: • indication for cardiac surgery • patient consent signed • elective surgery • age over 18 years • persistent postoperative bleeding defined as drainage loss of 100 ml / 30 min or more than 200 ml / h after arrival at the intensive care unit

Exclusion criteria

Exclusion criteria: • patient with preoperatively known treatment-relevant coagulation disorder (haemophilia A / B, APC-resistance, factor XIII deficiency, HIT-II, etc.) • pregnancy or breastfeeding

Design outcomes

Primary

Measure	Time frame
Primary endpoints are transfusion requirements regarding red blood cells, platelets, plasma, fibrinogen or pooled factors.	—

Secondary

Measure	Time frame
The secondary endpoints are 24-hour drainage loss, re-thoracotomy rate and cost analysis of blood and coagulation products.	—

Countries

Germany

Contacts

Public ContactMartin Haensig

Klinik für Herzchirurgie, Herzzentrum der Universität Leipzig

martin.haensig@zentralklinik.de+49 341 865-1423

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 1, 2026