I97.1 I25.1
Conditions
Interventions
Group 1: Since the design is observational for a diagnostic tool, there is only one arm: patients who undergo coronary artery bypass grafting with pre-operative severely reduced left ventricular eject
Sponsors
Universitätsklinikum Bonn
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients =18 years undergoing isolated, on-pump coronary artery bypass grafting 2. The surgery is elective or urgent (either planned or within one hospital admission between diagnosis and treatment), can be for STEMI/NSTEMI/ACS 3. Pre-operative Left ventricular function is 7.30) 7. The patient is normotensive on admission to ICU (Mean arterial pressure =60mmHg) 8. Upon admission to ICU, Cardiac index is =80% of the pre-operative value
Exclusion criteria
Exclusion criteria: 1. Manifest LCOS (see definition in primary endpoint section) upon admission to ICU 2. Central Venous Pressure =20mmHg on admission to ICU 3. Coronary artery bypass grafting was combined with other procedure (i.e. valve surgery) 4. Cardiac arrest with external cardiopulmonal resuscitation prior to admission to ICU 5. Patient is on extracorporal life-support or has an intra-aortic ballon pump (IABP) upon admission to ICU 6. Procedure was performed as salvage procedure (i.e. with cardiopulmonary rescucitation prior to initiating cardiopulmonary bypass, patient was unstable upon transfer to operating theatre “sliding on inotropes”)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Low cardiac output syndrome | — |
Secondary
| Measure | Time frame |
|---|---|
| - Pericardial tamponade - Acute renal failure (RIFLE criteria) - Myocardial ischemia with need for intervention/re-operation - Blood transfusions | — |
Countries
Germany
Contacts
Public ContactMiriam Silaschi
Universitätsklinikum Bonn
Outcome results
None listed