healthy subjects
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - no psychological or physical disorders or disabilities that are likely to cause fluctuations in cognitive performance during the study period - age is at least 18 years - eating behaviour is stable, i.e., either omnivore or vegetarian/vegan for at least 6 months - They have not taken creatine in the last 6 months before the study begins - They are able to consent - They do not consume on average more than 20g of alcohol per day (if female) or not more than 40g of alcohol per day (if male) - They do not consume recreational drugs more than once a week - They do not do more than 6 hours of intense sports per week
Exclusion criteria
Exclusion criteria: /
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Test scores in the two tests: - standardised 10-minute subtest of Raven Advanced Progressive Matrices - Wechsler auditory Backward Digit Span (BDS) task (Wechsler 1955) All participants are tested three times: At the beginning, after creatine supplementation and after placebo supplementation. We will test 120 participants. Participation ends for each participant after the third testing round. | — |
Secondary
| Measure | Time frame |
|---|---|
| We will conduct exploratory analyses for the following measures: D2 Test of Attention (Brickenkamp, 2002) Trail-Making-Test A (TMT-A) (Reitan, 1958) Block-Tapping-Test (BTT) (Schellig, 1997) Auditory Verbal Learning Test (AVLT, in German: VLMT, Helmstaedter & Durwen, 1990) Brief-visuospatial Memory Test –Revised (BVMT-R) Trail-Making-Test B (TMT-B) (Benedict, 1997) Stroop test (Farb-Wort-Interferenz Test, FWI-T, Bäumler, 1985) A test of verbal fluency called “Regensburger Wortflüssigkeitstest (RWT)” (Aschenbrenner, Tucha, Lange, 2000) Edinburgh Handedness Inventory (Oldfield, 1971) A test of crystallised intelligence called “Mehrfach-Wahl-Wortschatztest (MWT-B)” (Lehrl, 2005) | — |
Countries
Germany
Contacts
Universitätsklinikum Bonn