Chemical determination of AGE levels and serum concentrations of free light chains in hemodialysis patients compared to healthy subjects

Chemical determination of AGE levels and serum concentrations of free light chains in hemodialysis patients compared to healthy subjects - AGE and free light chains

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00017244

Enrollment

Registered

2019-05-28

Start date

2019-03-18

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

N18.5

Interventions

Group 1: Seven dialysis patients will be included who are hemodialyzed 3 times a week and have already been treated in a previous study (PERCI II) with a so-called "middle-cut-off" (MCO) dialysis memb

Eligibility

Sex/Gender

All

Age

40 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. No significant chronic diseases (e.g., diabetes mellitus, poorly controlled high blood pressure) 2. Participants in the PERCI II trial (for dialysis patients)

Exclusion criteria

Exclusion criteria: 1. Acute infection 2. Acute illness that prohibits participation in the study at the investigator's discretion 3. Women of childbearing potential who are not more than 2 years in menopause 4. Consent not given

Design outcomes

Primary

Measure	Time frame
There are no endpoints in this study. However, the concentrations of the AGE (Advanced Glycation Endproducts) and the free light chains kappa and lambda are determined. The analysis is done as a descriptive statistics and correlation.	—

Secondary

Measure	Time frame
see primary endpoint	—

Countries

Germany

Contacts

Public ContactRoman Fiedler

Universitätsklinikum Halle der Martin-Luther-Universität Halle-Wittenberg, Klinik für Innere Medizin II

roman.fiedler@uk-halle.de+493455572717

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026