Algesimetry under general anesthetic: Influence of intraoperative videopupillometry on opiate-dosing and postoperative cognitive dysfunction

Algesimetry under general anesthetic: Influence of intraoperative videopupillometry on opiate-dosing and postoperative cognitive dysfunction - Algesimetrie

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00017217

Enrollment

Registered

2019-06-07

Start date

2020-03-12

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients for (Hemi-)Thyroidectomy

Interventions

Group 1: Management of repetitive administration of the analgesic on the basis of established parameter. Group 2: Management of repetitive administration of the analgesic on the basis of the collected

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1) ASA (American Society of Anesthesiologists) I-III patients 2) surgical indication for partial/total thyroidectomy or surgical indication for parathyreoidektomie 3) surgical indication for elective surgery

Exclusion criteria

Exclusion criteria: 1) patients <18 years 2) missing informed consent 3) inability to participate in the evaluation of psychomotoric cognition 4) eye disease (diabetic retinopathy, glaucoma with mydriatic medication, ablatio retinae), post eye-operations 5) intracranial diseases (e.g. Tumors, aneurysms, cerebral edema) 6) Horner`s Syndrome, damage of sympathetic nerve fibers of cervical spine 7) ASA IV-V patients 8) dementia 9) patients suffering from chronic pain Syndrome and corresponding drug treatment

Design outcomes

Primary

Measure	Time frame
postoperative Cognitive Dysfunction (POCD-Test) 1. Test: preoperative in combination with the premedication-talks (3D CAM Assessment, Trail-making Test, Digital Symbol Substitution Test) 2. Test: postoperative 20-30 minutes after operation (3D CAM Assessment, Trail-making Test, Digital Symbol Substitution Test) 3. Test: postoperative not longer than 24 hours after operation ends (3D CAM Assessment, Trail-making Test, Digital Symbol Substitution Test)	—

Measure

Time frame

postoperative Cognitive Dysfunction (POCD-Test) 1. Test: preoperative in combination with the premedication-talks (3D CAM Assessment, Trail-making Test, Digital Symbol Substitution Test) 2. Test: postoperative 20-30 minutes after operation (3D CAM Assessment, Trail-making Test, Digital Symbol Substitution Test) 3. Test: postoperative not longer than 24 hours after operation ends (3D CAM Assessment, Trail-making Test, Digital Symbol Substitution Test)

—

Secondary

Measure	Time frame
postoperative usage of opioids, Pain-scores	—

Countries

Germany

Contacts

Public ContactDietrich Henzler

Universitätsklinik für Anästhesiologie, operative Intensivmedizin, Rettungsmedizin, Schmerztherapie, Campus OWL, Klinikum Herford AöR

dietrich.henzler@klinikum-herford.de+49 (0)5221 94 2481

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026