Diagnosis-related Outcomes in NeurocriTical care: Prognostic Estimate by health-care providers versus Risk scores in Intracerebral and Subarachnoid Hemorrhage

Diagnosis-related Outcomes in NeurocriTical care: Prognostic Estimate by health-care providers versus Risk scores in Intracerebral and Subarachnoid Hemorrhage - DON´T-PERISH

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00017203

Enrollment

1000

Registered

2019-05-13

Start date

2019-06-12

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I60

Interventions

Group 1: One observational Group, in which prognosis at 48 h, 7 and 14 days after symptom onset get determined through prognostic scales and the treating physician and nurse are questioned about their

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with spontaneous intracerebral hemorrhage (ICH) and non-traumatic subarachnoid hemorrhage (SAH) admitted to centers with expertise in Neurocritical care

Exclusion criteria

Exclusion criteria: - No knowledge of German and English language - Withdrawal of care during acute hospitalization according to advanced directives - Admission more than 48 hours after symptom onset - Hemorrhage due to trauma

Design outcomes

Primary

Measure	Time frame
Functional outcome at 6 months Modified Rankin Scale dichotomized 0-2 versus 3-6 per telephone interview [Time Frame: 6 months]	—

Secondary

Measure	Time frame
Functional outcome at 3 months Modified Rankin Scale dichotomized 0-2 versus 3-6 per telephone interview [Time Frame: 3 months] Functional outcome at 6 months Modified Rankin Scale dichotomized 0-3 versus 4-6 per telephone interview [Time Frame: 6 months] Functional outcome at 3 months Modified Rankin Scale dichotomized 0-3 versus 4-6 per telephone interview [Time Frame: 3 months] Quality of life Short Form Health Survey Short Form (SF)-36 (written questionaire or telephone interview) [Time Frame: 3 and 6 months] Quality of life Sickness Impact Profile Sickness Impact Profile (SIP) (written questionaire or telephone interview) [Time Frame: 3 and 6 months] Cognitive outcome Telephone Interview for Cognitive Status per telephone interview Telephone Interview for Cognitive Status (TICS) [Time Frame: 3 and 6 months]	—

Measure

Time frame

Functional outcome at 3 months Modified Rankin Scale dichotomized 0-2 versus 3-6 per telephone interview [Time Frame: 3 months] Functional outcome at 6 months Modified Rankin Scale dichotomized 0-3 versus 4-6 per telephone interview [Time Frame: 6 months] Functional outcome at 3 months Modified Rankin Scale dichotomized 0-3 versus 4-6 per telephone interview [Time Frame: 3 months] Quality of life Short Form Health Survey Short Form (SF)-36 (written questionaire or telephone interview) [Time Frame: 3 and 6 months] Quality of life Sickness Impact Profile Sickness Impact Profile (SIP) (written questionaire or telephone interview) [Time Frame: 3 and 6 months] Cognitive outcome Telephone Interview for Cognitive Status per telephone interview Telephone Interview for Cognitive Status (TICS) [Time Frame: 3 and 6 months]

—

Countries

Germany

Contacts

Public ContactKatja Wartenberg

Klinik für NeurologieUniversitätsklinikum Leipzig

katja.wartenberg@medizin.uni-leipzig.de+49 341 97 20072

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026