E20.0
Conditions
Interventions
Group 1: Calcium 3 x 500mg per os and Magnesium1 x 375mg per os over 14 days prior to surgery
Group 2: no Calcium or Magnesium taking
Sponsors
Universitätsklinik für Viszeralchirurgie, Pius-Hospital Oldenburg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age of majority,gender-independent all patients who are planned to undergo total thyroidectomy for validation of the ThyPRO-39 questionnaire, gender-independent all patients who are planned to undergo thyroid surgery
Exclusion criteria
Exclusion criteria: Patients younger than 18 years of age poor German language skills Incompliance in calcium and magnesium intake taking thiazide diuretics or lithium Patients with recurrent surgery Refusal to participate in the study Chronic renal insufficiency Preexisting hyperparathyroidism with hypercalcemia Retirement by patient request
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of life (using questionnaire ThyPRO-39, EQ-5D-5L) at 4 different times: 2 weeks before surgery, immediately before surgery at inpatient admission, before discharge from hospital and 6 weeks after surgery; Severity of postoperative paraesthesia (by means of query) during inpatient stay after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Analysis of the relationship between preoperative calcium and magnesium administration and the occurrence of paraesthesia symptoms Change in postoperative calcium value Validation of the thyroid specific questionnaire ThyPRO-39 | — |
Countries
Germany
Contacts
Public ContactDennis Fried
Universitätsklinik für Viszeralchirurgie, Pius-Hospital Oldenburg
Outcome results
None listed