Yoga in the treatment of Panic disorder and/or Agoraphobia

Yoga in the treatment of Panic disorder and/or Agoraphobia - YOPA

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00017135

Enrollment

Registered

2019-04-15

Start date

2019-04-18

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F41.0 F40.00

Interventions

Group 1: Yoga-intervention: Participants allocated to this arm will take part in an 8-week vinyasa yoga-program comprising of dynamic movements, strengthening body positions, rhythmic breath regulati

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Primary diagnosis of panic disorder and/or agoraphobia (ICD-10), PAS-value not less than 9 and not more than 39.

Exclusion criteria

Exclusion criteria: Pregnancy, medical contraindications for regular yoga training, severe comorbidities, acute suicidality, changes in psychcopharmaceutic treatment within the past month, current psychotherapy, regular yoga practice within the past 3 month

Design outcomes

Primary

Measure	Time frame
Improvement of clinical symptomatology measured by means of the Panic- and Agoraphobia-scale (PAS; Bandelow, 1999). Time of measurements are at baseline, after 4 weeks and post intervention (after 8 weeks). For exploratory analyses, a 3 month follow-up measurement will take place.	—

Secondary

Measure	Time frame
Secondary outcomes will be measured at the above mentioned timepoints. To investigate changes in the physiological stress response, heart-rate variability (HRV), salivary cortisol and salivary alpha-Amylase will be measured. Furthermore, anxiety-specific outcomes will be measured by means of validated self-report questionnaires: Body Sensation Questionnaire (BSQ, Chambless 1984), Mobility Inventory (MI, Chambless 1984), Agoraphobic Cognitions Questionnaire (ACQ, Chambless 1984), Anxietysensitivity Index (ASI, Taylor 1998) will be evaluated. To tap into more general symptomatology the clinical global impression (CGI, Guy 1976), as well as the Beck Depression Inventory (BDI-II, Beck, Steer, & Brown, 1996) will be implemented. For further exploration of relevant mechanisms, psychological constructs, such as mindfulness, psychological flexibility, emotion regulation, wellbeing, stress perception, sport specific and motivational aspects will be measured. To evaluate short-term effects of Yoga training, the State-Trait-Anxiety-Inventory (STAI-S) and the mental state scale of Basel (BBS) will be utilized pre and post yoga classes.	—

Measure

Time frame

Secondary outcomes will be measured at the above mentioned timepoints. To investigate changes in the physiological stress response, heart-rate variability (HRV), salivary cortisol and salivary alpha-Amylase will be measured. Furthermore, anxiety-specific outcomes will be measured by means of validated self-report questionnaires: Body Sensation Questionnaire (BSQ, Chambless 1984), Mobility Inventory (MI, Chambless 1984), Agoraphobic Cognitions Questionnaire (ACQ, Chambless 1984), Anxietysensitivity Index (ASI, Taylor 1998) will be evaluated. To tap into more general symptomatology the clinical global impression (CGI, Guy 1976), as well as the Beck Depression Inventory (BDI-II, Beck, Steer, & Brown, 1996) will be implemented. For further exploration of relevant mechanisms, psychological constructs, such as mindfulness, psychological flexibility, emotion regulation, wellbeing, stress perception, sport specific and motivational aspects will be measured. To evaluate short-term effects of Yoga training, the State-Trait-Anxiety-Inventory (STAI-S) and the mental state scale of Basel (BBS) will be utilized pre and post yoga classes.

—

Countries

Germany

Contacts

Public ContactAnna Dania Esch

Charité - Universitätsmedizin Berlin Klinik für Psychiatrie und Psychotherapie Campus Charité Mitte

yopa-studie@charite.de030450517187

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026