Effect of different application regimes of tranexamic acid on perioperative blood loss in total knee arthroplasty

Effect of different application regimes of tranexamic acid on perioperative blood loss in total knee arthroplasty - TXA in TKA

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00017095

Enrollment

1500

Registered

2021-08-19

Start date

2021-03-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

M17

Interventions

Group 1: Patients who underwent primary total knee arthroplasty between 2019 and 2021 under the administration of tranexamic acid

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Primary total knee arthroplasty under the use of tranexamic acid

Exclusion criteria

Exclusion criteria: none

Design outcomes

Primary

Measure	Time frame
Estimated perioperative blood loss using pre- and postoperative lab values	—

Secondary

Measure	Time frame
Acute postoperative pain intensity (numeric rating scale 0-10) and mobility (range of motion, walking skills) assessed by the hospital's physiotherapists who were completely blinded to the application regime of tranexamic acid. Long-term follow up by PROMS (WOMAC-Score) after 3 and 12 months.	—

Countries

Germany

Contacts

Public ContactAxel Jakuscheit

Orthopädische Klinik König-Ludwig-Haus

a-jakuscheit.klh@uni-wuerzburg.de0049 931 803 0

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026