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Quantitative EEG as biomarker for the prediction of seizures, depression and cognitive decline after stroke - A substudy to the Berling Longterm Observation of Vascular Events - BeLOVE - Study

Quantitative EEG as biomarker for the prediction of seizures, depression and cognitive decline after stroke - A substudy to the Berling Longterm Observation of Vascular Events - BeLOVE - Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00017079
Enrollment
625
Registered
2019-05-15
Start date
2019-03-20
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I63.9 G40.9

Interventions

Group 1: Patients receive an EEG measurement with dry electrode EEG caps within seven days of a cerebrovascular event. In study visits after 90 days and two years and in anual telephone interviews, pa

Sponsors

Charité Campus Benjamin Franklin
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: acute cerebrovascular disorders (trigger event), defined by: i) a transient ischemic attack (TIA) with clinical restitution within 24h AND initial neurological deficit verified by a neurologist OR ABCD2-Score >= 3 OR visibleDWI-lesion (MRI) OR the main hospital diagnosis of Amaurosis fugax ii) Ischemic stroke including retinal central artery occlusion iii) stroke caused by non-traumatic intracerebral hemorrhage iv) stroke caused by cerebral venous thrombosis

Exclusion criteria

Exclusion criteria: Epileptic seizure prior to the event leading to inclusion in the study

Design outcomes

Primary

MeasureTime frame
1st: Development of seizures, diagnosed using Epilepsy-Screening questionnaire by Ottman et al. 2nd: Development of Post-Stroke Depression using PHQ-9 questionnaire 3rd: Development of post-stroke cognitive decline using Montreal cognitive assessment (MOCA)-test

Secondary

MeasureTime frame
Development of acute symptomatic seizures within 7 days after the cerebrovascular event

Countries

Germany

Contacts

Public ContactJakob Dörrfuß

Charité Universitätsmedizin BerlinKlinik für Neurologie

jakob.doerrfuss@charite.de030450543628

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026