Capillary Leak Syndrome
Conditions
Interventions
Group 1: Patients undergoing cardiac and/or vascular surgery are to be studied during their intensive care treatment on a daily basis.
Sponsors
Klinik für Anästhesiologie und Intensivmedizin, Uniklinik Freiburg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Cardiac and/or vascular surgery 2. Age =18 3. Consent of the patient, of next-of-kin or legal guardian
Exclusion criteria
Exclusion criteria: 1. Refusal to participate of the patient, of next-of-kin or legal guardian 2. Idiopathic Capillary Leak Syndrome (ICLS, "Clarkson's Disease") 3. HIV infection 4. Viral hepatitis 5. Hereditary C1-esterase deficiency 6. Recurrent Angioedema 7. Pre-existing chronic kidney failure on requiring dialysis 8. Pre-existing hepatic impairment with MELD score = 20 9. Participation in pharmacological trials
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| No a priori definition of a primary endpoint is possible in the described study. Goal of this study is to characterize parameters, which may indicate CLS in cardiovascular surgery patients. The occurrence of CLS is evaluated by an experienced critical care physician and scored according to clinical as well as study parameters. | — |
Countries
Germany
Contacts
Public ContactJakob Wollborn
Klinik für Anästhesiologie und Intensivmedizin, Uniklinik Freiburg
Outcome results
None listed