Parkinson-Syndrome,dystonia, ataxia, hyperkinetic movement disorders,sensory-driven movement disorders (polyneuropathy, vestibular loss) motor abnormalities
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: -Male or female patients/ healthy controls -Patients: Patients with symptoms of a neurological motor disorder (neurodegenerative, sensory loss) -Age: = 18 years -Signed informed consent
Exclusion criteria
Exclusion criteria: -Acute psychotic syndrome -Incapability to sign informed consent -Medication or concomitant disease, that restricts the usability of the scientific data (decision is up to the principal investigator) -Control subject with impairment of the lower extremities (Arthrosis, Hip/Knee TEP (<5 years)) -Any additional disease which impairs stance and gait in a relevant way
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Motor deficite measure [Skale 0 – 1; 0= healthy, 1=extrem symptoms] | — |
Secondary
| Measure | Time frame |
|---|---|
| Movement analysis (vision-based) Gait speed [m/sec], Gait speed increase (%), Cadence [n/min], Step time [s], Stride time [s] Step length [cm] Stride length [cm] Base width [cm] Swing phase [% of gait cycle] Stance phase [% of gait cycle] Double support time [% of gait cycle] Speed variability [%] Step length variability [%] Stride length variability [%] Stride time variability [%] Angular changes [°] Smoothness (Hand movement and walking) Number of tapping [N] Posturography Spontaneous sway measures (cm) Body reactions following external perturbation (gain, phase, model parameters) Disease/syndrome specific motor score: Fear of falling: - Falls Efficacy Scale International (FES-I) Disease/syndrome specific motor score: - Unified Parkinson’s Disease Rating Scale (UPDRS), part III - EURO- HD Huntington’s Disease rating scale, part III - Marsden Fahn Tremor rating scale - Abnormal involuntary movement rating scale (AIMS) Walking ability: - Tinetti (POMA) Scores for cognitive impairments: - MOCA | — |
Countries
Germany
Contacts
Universitätsklinik FreiburgKlinik für Neurologie und Neurophysiologie - klinische Forschung