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Validation of German versions of the "Cerebellar Cognitive Affective Syndrome" Scale in patients with degenerative and focal cerebellar disorders.

Validation of German versions of the "Cerebellar Cognitive Affective Syndrome" Scale in patients with degenerative and focal cerebellar disorders. - German CCAS Scales

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00016854
Enrollment
600
Registered
2019-03-01
Start date
2019-01-25
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

degenerative ataxias, focal cerebellar lesions after hemorrhage, ischaemic stroke, tumor or surgery on/in the cerebellum I63 R27.0 G11 D33 C71

Interventions

Group 1: degenerative ataxias: application of the following scales/assessments: I. CCAS Scale version A, B, C or D. In a subgroup of patients testing with one version of the scale twice a) by the s

Sponsors

Neurologische Klinik, Universitätsklinikum Essen
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Written consent. 2. Minimum age 18 years. 3. German-speaking.

Exclusion criteria

Exclusion criteria: 1. Healthy control subjects: Neurological disorders (inclusive epileptic seizures) or psychiatric conditions. 2. Patients: Severe psychiatric conditions. 3. Drug or alcohol abuse. 4. Intake of centrally acting drugs. 5. Persons with consuming disorders and in reduced general health condition. 6. (Adult) persons that have a legal guardian and that are not contractually capable.

Design outcomes

Primary

MeasureTime frame
Validation of the versions A-D of the German CCAS Scale. After data acquisition the following parameters are determined for this purpose: - re-test-reliability - interrater-reliability - parallel-test-reliability - internal consistency - construct-validity - sensitivity - specifity

Secondary

MeasureTime frame
1. Pattern of cognitive/affective deficits in different cerebellar disorders 2. Correlation of cognitive/affective deficits in patients with focal cerebellar lesions to lesion sites shown by MRI (lesion-symptom-mapping) in following trials

Countries

Germany

Contacts

Public ContactAndreas Gustafsson Thieme

Neurologische Klinik, Universitätsklinikum Essen

andreas.thieme@uk-essen.de0201-723-83221

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 25, 2026