Mechanisms and predictors of pain resolution in complex regional pain syndrome (CRPS) and chronic postsurgical inguinal pain

Mechanisms and predictors of pain resolution in complex regional pain syndrome (CRPS) and chronic postsurgical inguinal pain - ResolvePain CRPS CPIP

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00016790

Enrollment

300

Registered

2019-02-20

Start date

2018-10-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Causalgia or CPRS M89.0 G57.8 G56.4

Interventions

Group 1: CRPS type I or II, upper and lower extremity in a long-term observation with advanced diagnostics such as questionnaires, biomarkers in the blood and skin tissue as well as changes in dorsal

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: CRPS or chronic inguinal pain

Exclusion criteria

Exclusion criteria: Lack of the ability to give informed consent ; contraindications to the procedure for an MRI examination, such as the presence of metal foreign bodies, e.g. pacemakers, paramagnetic vascular clips, garnet splinters, metallic endoprosthesis; pregnancy; claustrophobia, contrast media intolerance, terminal renal insufficiency and acute renal failure, severe asthma.

Design outcomes

Primary

Measure	Time frame
Expression of a cell adhesion molecule in the skin	—

Secondary

Measure	Time frame
Alterations in microRNAs, altered permeability in DRGs	—

Countries

Germany

Contacts

Public ContactHeike Rittner

Zentrum für interdisziplinäre Schmerzmedizin

rittner_h@ukw.de49 931 201 30251

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 6, 2026