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Tolerance induction through early feeding to prevent food allergy in infants with eczema

Tolerance induction through early feeding to prevent food allergy in infants with eczema

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00016770
Enrollment
150
Registered
2020-01-09
Start date
2020-02-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

T78.1 L20.9

Interventions

Group 1: Infants, Age 4-8 months, with eczema, receiving daily rust-like biscuits containing small amounts of hen´s egg, cow´s milk, peanut and hazelnut Group 2: Infants, Age 4-8 months, with eczema,

Sponsors

Charité Campus Charité Mitte
Lead Sponsor

Eligibility

Sex/Gender
All
Age
4 Months to 6 Months

Inclusion criteria

Inclusion criteria: 1. children, age 4-8 months 2. eczema 3. signed informed consent of parents

Exclusion criteria

Exclusion criteria: - previous consumption of hen´s egg, peanut or hazelnut - wheat allergy - severe diseases (cardiac, congenital) - participation in another interventional Trial

Design outcomes

Primary

MeasureTime frame
Food allergy to at least on one of the following Foods: hen´s egg, cow´s milk, hazelnut and peanut at around one year of age.

Secondary

MeasureTime frame
1. Allergic reactions during Intervention 2. Multiple food allergies, bronchial asthma, changes in disease severity of eczema 3. Changes of the microbiome (Skin and gut), changes in immunological processes 4. Identification of genetic and epigenetic factors associated with Food allergy 5. Identification of biomarker characterizing anaphylactic reactions

Countries

Germany

Contacts

Public ContactKirsten Beyer

Charité Campus Virchow-Klinikum

kinderallergie-studien@charite.de+49 30 450566037

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 12, 2026