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Prevention of dental erosions by rinsing with calcium and fluoride containing solutions

Prevention of dental erosions by rinsing with calcium and fluoride containing solutions

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00016757
Enrollment
12
Registered
2019-02-18
Start date
2019-12-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K03.2

Interventions

Group 1: Investigation, if rinsing with a calcium or fluoride containing solution prior to an erosive attack reduces the softening of the eroded enamel. Group 2: No rinsing with a test solution before

Sponsors

Universität Zürich, Zentrum für Zahnmedizin, Klinik für Präventivzahnmedizin, Parodontologie und Kariologie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Age of at least 18 years, written informed consent, willingness and ability to meet the requirements of the study plan, healthy participants will be included in the study

Exclusion criteria

Exclusion criteria: Age under 18 years, non-compliance, current orthodontic treatment hampering the insertion of an intraoral appliance, simultaneous participation in another clinical study, alcohol or drug addicts, heavy smokers (>10 cigarettes/day), patients with known allergies against products to be used in the study or patients with hyposalivation (stimulated: <1.0 ml/min; unstimulated: <0.25 ml/min)

Design outcomes

Primary

MeasureTime frame
Investigation, if rinsing with a calcium or fluoride containing solution prior to an erosive attack reduces the softening of the eroded enamel. Assessment of enamel softening through repeated microhardness measurement (?KHN) - before start of the experiment (initial microhardness) and after rinsing with the respective test solution followed by erosion.

Secondary

MeasureTime frame
no further outcome

Countries

Switzerland

Contacts

Public ContactFlorian Wegehaupt

Universität Zürich, Zentrum für Zahnmedizin, Klinik für Präventivzahnmedizin, Parodontologie und Kariologie

florian.wegehaupt@zzm.uzh.ch+41 (0)44 634 3354

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026