G25.0 G20.9
Conditions
Interventions
Group 1: Procedure:
1. Study MRI with DTI, Resting State, Task-based fMRI as well as Clinical Testing and Electro-neurography before clinically indicated MRgFUS therapy
2. Study MRI with DTI, Resting
Sponsors
Universitätsklinik Bonn: NeuroRadiologische Klinik, Radiologische Klinik, Klinik für Neurologie, Neurochirurgische Klinik Hauptverantwortliche der Studie: Prof. Dr. U. Wüllner, Prof. Dr. H. Vatter, Prof. Dr. H. Boecker, Prof. Dr. A. Radbruch
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: both sexes, Age 18 and older, patients with a proven movement disorder of the head (tremor, dystonia) or motoric restlessness, who can tolerate the clinically established MRgFUS therapy and are suitable for it Ability of the patient to give informed consent, MRI capability according to the safety standards defined for the study clinic
Exclusion criteria
Exclusion criteria: Deviation from inclusion criteria, withdrawal of consent, patients who do not meet the criteria for a safe MRI, or who would otherwise be classified as having a high risk according to the general hospital MRI check result, patients included in the screening questionnaire have found MRI or study participation to be a burden.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Observational study without classic endpoint. Aims: 1. Identify optimal thalamic therapy point in the brain for future MRgFUS therapies 2. to individualize the therapy to the individual patient (optimization of the therapy point, the delivered amount of energy, the point size related to the tremor shape / diagnosis) 3. Generate long-term findings regarding the outcome according to MRgFUS. | — |
Secondary
| Measure | Time frame |
|---|---|
| see above | — |
Countries
Germany
Contacts
Public ContactUllrich Wüllner
Sektion Bewegungsstörungen Klinik und Poliklinik für Neurologie Universitätsklinikum Bonn
Outcome results
None listed