Impact of environment and kinesic behavior on genetic factors, brain structure and function and condition in people from young age onwards and possible development of psychiatric disorders
Conditions
Interventions
Group 1: Child: 7-11
Teenager: 12-17
Adult: 18-65
(Questionnaires, biological samples, 7-days ambulatory assessment, MRI-testing (only teenager and adults))
Sponsors
Zentralinstitut für Seelische Gesundheit
Eligibility
Sex/Gender
All
Age
7 Years to 65 Years
Inclusion criteria
Inclusion criteria: Sufficient level of German or Arabic language; Ability to understand the study protocol and to give an informed consent; Will to use the device for ambulatory assessment
Exclusion criteria
Exclusion criteria: General exclusion criteria: 1) Subjects who spent most parts of their days outside of the target area (target areas are for example municipal district: Mannheim, Heidelberg und Ludwigshafen; administrative distric: Rhein-Neckar-Kreis/""most parts of their days"" means: habitation of a secondary residence, school/work place or facilities visited [""Auspendler""], current location outside the target region, short stays outside the target area for two or more days per week) 2) chronic endocrinological, cardiovascular, immunological und clinically manifest psychiatric disorder 3) acute diseases Exclusion criteria for MRI 1) regular intake of medicaments containing glucocorticoids 2) Drug abuse 3) Pregnancy 4) objects from metal in head or body (e.g. vascular clamps, metal prostheses, artificial heart valves, tiling, nails, wires, shrapnel, medication pump or other implants) 5) operation of heart or brain in medical history 6) therapeutic patches (nicotine, hormone, or against pain) 7) epilepsy 8) piercings which are not removable 9) Accident with unconsciousness in medical history 10) Claustrophobia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Longitudinal study to search for epidemiological factors and investigate the impact of the environment, stress and functional and structural brain development. All participants should attend three times for an MRI-testing to investigate long-term modifications. | — |
Countries
Germany
Contacts
Public ContactBeate Höchemer
Zentralinstitut für Seelische Gesundheit
Outcome results
None listed