L40 R60
Conditions
Interventions
Group 1: Randomized single-sided analysis (one leg: therapy with standard of care and compression therapy, the other leg: only standard of care therapy)
Therapy with standard of care and compression
Sponsors
Universitätsklinikum Essen
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Age = 18 - Psoriasis vulgaris for at least 6 months - edema on both lower legs - Psoriatic plaques on both lower legs - Patient must be able to put compression stockings on and off by her- or himself.
Exclusion criteria
Exclusion criteria: - Inadequate ability to communicate in the German language or lack of comprehension of the German language or dementia or (functional) illiteracy - Lack of or unwillingness to sign the informed consent form - Decompensated heart failure - Advanced polyneuropathy - Pregnancy and breast feeding period - Critical ischemia, KADI (ankle-brachial pressure index) 40
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The clinical response of psoriatic plaques at the lower legs comparing both sides (standard of care vs. standard of care and compression) as measured by PASI (Psoriasis Area and Severity Index) and BSA (Body Surface Area) and LSS (Lesion Severity Score) after four weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| The health-related quality of life, overall and in relation to the research question (DLQI (Dermatology Life Quality Index) measurement) - The development of any pain on the lower legs (VAS (Visual Analogue Scale)) - The development of leg circumference / lower leg edema (circumferential measurement by defined measuring points) - The satisfaction / experience with the compression therapy from the patient's point of view (as assessed by questionnaire) All endpoints will be assessed after 4 weeks. | — |
Countries
Germany
Contacts
Public ContactWiebke Sondermann
Universitätsklinikum Essen (AöR), Klinik für Dermatologie, Venerologie und Allergologie
Outcome results
None listed