adverse childhood experience
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: between 18 and 60 years old before the 18th birthday physical or sexual violence or neglect currently no drug intake
Exclusion criteria
Exclusion criteria: Pregnancy, Alcohol dependency; abstinence less than 2 years Alcohol abuse; abstinence less than 1 month, Drug consumption Lifetime or current diagnosis of schizophrenia Lifetime or current diagnosis of Bipolar 1 disorder Psychotropic medication except of SSRI/SNRI No sufficient knowledge of the German language Acute endangerment of self and others Organic and degenerative disease of the brain Severe internal or neurological diseases Central exclusion criteria for (f)MRI
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Regarding the primary outcome pain modulation, fear conditioning and empathy for pain are analysed via fMRI measurement. | — |
Secondary
| Measure | Time frame |
|---|---|
| The following questionnaires serve as secondary outcome: - Symptomchecklist (Franke et al., 2011) - German version of the Childhood Trauma Questionnaire (CTQ) (Bernstein et al., 2003) - Resilience Scale (Schumacher et al., 2005) - The Connor-Davidson Resilience Scale (CD-RISC; Connor & Davidson, 2003) - KERF - German version of the Maltreatment and Abuse Chronology of Exposure (MACE) Interviews (Teicher & Parigger, 2015) - HADS (Hospital Anxiety and Depression Scale) (german version R. P. Snaith und A. S. Zigmond 2011) - NEO Personality Inventory, (P. T. Costa & R. McCrae) - Borderline Symptom List (BSL-23) (Bohus et al. 2009) - State-trait-anxiety inventory (Laux et al., 1981) - Trier inventory for assessment of chronic stress (Schulz and Schlotz, 1999) - The Fear of Pain Questionnaire (Asmundson, Gordon & V Bovell,2008) - Interpersonal Reactivity Index (IRI) (Davis et al. 1983) - Empathy for Pain Scale (EPS) (Giummarra 2014) - Modified form of the questionnaire for assessment of computergaming behavior (Wölfling, Müller & Beutel, 2010) | — |
Countries
Germany
Contacts
ZI Mannheim