K74
Conditions
Interventions
Group 1: Eight patients with end stage liver disease (3 males and 5 females) their age ranged from 45-60 years, who received a portal vein infusion of autologous bone marrow mononuclear cells (which i
Sponsors
Faculty of medicine-Tanta University
Eligibility
Sex/Gender
All
Age
45 Years to 60 Years
Inclusion criteria
Inclusion criteria: All male or female patients aged from 40 to 60 years with evidence of liver decompensation as ascites, low prothrombin time less than 50%, low serum albumin less than 2.5 g/dl, past history of hepatic encephalopathy were included in the study
Exclusion criteria
Exclusion criteria: Pregnant or lactating females, patients with recent gastrointestinal bleeding (one month), hepatocellular carcinoma, spontaneous bacterial peritonitis, an evidence of human immunodeficiency virus, any life threatening infection, having history of hypersensitivity to G-CSF and those included in any other clinical trials within the previous month were excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| What? - Improvement of clinical, biochemical and radiological characteristics How? -Both groups were subjected to: complete history taking, clinical examination (ascites, jaundice, and Lower Limb edema), Abdominal U/S , and laboratory investigations: serum bilirubin, ALT, AST, albumin, INR, with estimation of the degree of ascites, encephalopathy and Child-Pugh Class. When? - All of these clinical, laboratory and radiological investigations were performed before treatment (baseline) and after 1, 3 and 6 months of treatment (follow up). | — |
Countries
Egypt
Contacts
Public ContactDina Abo Rayia
Faculty of medicine-Tanta University
Outcome results
None listed