K74.6
Conditions
Interventions
Group 1: Patients without cirrhosis
After study inclusion we perform measurements of metabolic compounds of breathing air with a MOX gas sensor. This will serve as a reference for study arms 2 to 4. T
Sponsors
Universitätsklinikum Jena
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Diagnosis of liver cirrhosis according to Imaging, clinical criteria or histology (except for control Group without cirrhosis), Age > 18 yrs, written informed consent
Exclusion criteria
Exclusion criteria: • known malignancy • mechanical biliary obstruction • uncontrolled Diabetes mellitus • severe respiratory disease (pneumonia, COPD GOLD =III, Asthma bronchiale) • chronic kidney injury KDIGO =3 • congestive heart failure NYHA =3 • symptomatic coronary heart disease • peripheral arterial occlusive disease Fontaine =IIa
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Death or LTX (Liver transplantation) at 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| New decompensation during 12 weeks New ACLF (Acute-on-chronic liver failure) according to EASL-CLIF Criteria during 12 weeks | — |
Countries
Germany
Contacts
Public ContactPaul Horn
Klinik für Innere Medizin IV Universitätsklinikum Jena
Outcome results
None listed