Negative effects of weightlessness on the human body, associated with muscle atrophy, reduction of cardiovascular performance, bone density loss, neurovestibular changes.
Conditions
Interventions
Group 1: 12 healthy male and female participants
Neuromuscular exercises
Warm-up without centrifugation
• 10 Heel raises
• 10 Squats
• 10 Jumps
Training with centrifugation
CORE-Training
3 sets of
•
Sponsors
DLR - Institut für Luft- und RaumfahrtInstitut für Luft- und Raumfahrtmedizin
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: - Healthy males and females - age 18-45 years - BMI 18-25 - Body weight <100 kg - Body height 170 – 210 cm - VO2max = 35ml/kg/min - Successful completion of screening examination - Ability to complete all necessary tests and exercises - Centrifuge experienced subjects - signed informed consent Form
Exclusion criteria
Exclusion criteria: - Additional physical exercises during the study - Drug or alcohol abuse (regular consumption of > 20g alcohol / day) - Alcohol: no ingestion within 12 hours of start of study - pregnancy (positive pregnancy test) - Current muscle or joint disease - Diabetes mellitus - Herniated disc - chronic back pain - Use of psychotropic drugs and any other drugs that may affect the study experiments. - Heart disease or a cardiac pacemaker. - Abnormal blood pressure (above 140/90 mmHg or below 90/60 mmHg) - Severe orthostatic intolerance or impaired neurovestibular function. - Kidney disease (Deviations from normal values of creatinine in plasma; Creatinine normal value < 1.20 mg / dL) - Thyroid dysfunction ( deviations from normal values for TSH in plasma; normal values TSH 0,27 - 4,20 mU / l) (a laboratory examination carried out only in case of suspicion of dysfunction) - Anemia (Hb lower the normal value; standard value Hb men : from 13.5 to 17.5 g / dL; women : from 12.0 to 15.7 g / dL ) - History of epileptic seizures
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Completion of every AG session without medical termination due to syncope average Wong-Baker Pain rating of = 4 | — |
Secondary
| Measure | Time frame |
|---|---|
| • Measurement of cardiovascular loading (heart rate and blood pressure) • Assessment of pain and perceived exhaustion induced by cross-coupled sensations during centrifugation compared with control by questionnaires (Wong-Baker, RPE) • Recording of muscle activation of erector spinea group, quadriceps (rectus femoris, vastus medialis, intermedius and lateralis), m. gastrocnemius) on centrifuge compared with control • Recording of ground reaction forces during jumping on centrifuge compared with control | — |
Countries
Germany
Contacts
Public ContactTimo Frett
DLR-Institut für Luft und Raumfahrtmedizin
Outcome results
None listed