Liver fibrosis, Liver cirrhosis, Hepatocellular carcinoma, Colon carcinoma metastasis, Cholangiocarcinoma K74 C22 C78
Conditions
Interventions
Group 1: Patients, scheduled for liver surgery, were included and examined with LiMAx (13C-Methacetin Liver Maximum capacity) and THE (time-harmonic ultrasound elastography), as well as blood samples
assessment of serological markers
Sponsors
Charité Campus Virchow-Klinikum
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Healthy test person = 18 years old; Patients = 18 years old admitted to the hospital for liver surgery or liver transplantation; Participants who gave their written informed consent
Exclusion criteria
Exclusion criteria: Patients with history of liver transplantation; Patients with a portosystemic shunt; Patients with a known paracetamol allergy; Patients with known coronary heart disease; Patients with severe infectious disease or fever >38.5°; Patients who are unable to cooperate during the study (e.g. mental dysfunction or drug abuse)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| liver function / structure relationship (function assessed at enrollment by the Liver MAximum capacity (LiMAx) test and tissue stiffness by 2D time-harmonic elastography (THE)) | — |
Secondary
| Measure | Time frame |
|---|---|
| Influence of the bicarbonate kinetic on the result of the LiMAx liver function test | — |
Countries
Germany
Contacts
Public ContactTilo Wuensch
Chirurgische Klinik Campus Virchow-Klinikum CVK
Outcome results
None listed