Exploring the long-term impact of early life adversity on the (anti-)social brain

Exploring the long-term impact of early life adversity on the (anti-)social brain - MARS T11

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00016359

Enrollment

280

Registered

2019-01-17

Start date

2018-09-30

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vulnerability to stress-related antisocial disorders F91

Interventions

Group 1: The investigation will be performed in participants from the Mannheim Study of Children at Risk. The MARS is prospective longitudinal study of an epidemiological cohort followed since birth.

Eligibility

Sex/Gender

All

Age

32 Years to 35 Years

Inclusion criteria

Inclusion criteria: participants of the Mannheim Study of Children at Risk

Exclusion criteria

Exclusion criteria: metal implants or other MRI contraindications

Design outcomes

Primary

Measure	Time frame
Effects of early adversity and protective factors on brain morphology and function implicated in the processing of social information. Specifically, we will investigate: 1) real-life quantitz and quality of social interactions via smartphone, 2) brain volume, surface area and cortical thickness, 3) BOLD response during the following tasks: empathy, emotion regulation, stop signal, reward, passive avoidance, cyberball and dictator game.	—

Measure

Time frame

Effects of early adversity and protective factors on brain morphology and function implicated in the processing of social information. Specifically, we will investigate: 1) real-life quantitz and quality of social interactions via smartphone, 2) brain volume, surface area and cortical thickness, 3) BOLD response during the following tasks: empathy, emotion regulation, stop signal, reward, passive avoidance, cyberball and dictator game.

—

Countries

Germany

Contacts

Public ContactNathalie Holz

nathalie.holz@zi-mannheim.de0621 1703 4904

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026