Sex- and Gender-sensitive prevention of cardiovascular and metabolic disease in older adults in Germany

Sex- and Gender-sensitive prevention of cardiovascular and metabolic disease in older adults in Germany - GendAge

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00016157

Enrollment

1250

Registered

2019-04-03

Start date

2018-05-22

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The GendAge study explores mechanisms of disease development with respect to sex differences and considers socio-cultural factors. The study focuses on cardio-metabolic disease. As part of the GendAge study, a follow-up medical examination of the older sub-population of the Berlin Aging Study (BASE-II) is conducted. BASE-II studies physical, psychological and social factors, which impact healthy aging.

Interventions

Group 1: Observational study (The GendAge study explores mechanisms of disease development with respect to sex differences and considers socio-cultural factors. The study focuses on cardio-metabolic d

Eligibility

Sex/Gender

All

Age

64 Years to 94 Years

Inclusion criteria

Inclusion criteria: Participants were eligible for inclusion in the GendAge cohort, if they had taken part in the first-wave study (BASE II), belonged to the older age-group of BASE II (N=1600, mean age 68,2 ±3,7 years) and provided written informed consent. The BASE II is a classic convenience sample of 60 to 80 year olds (older age group, baseline), drawn from the Berlin metropolitan area.

Exclusion criteria

Exclusion criteria: /

Design outcomes

Primary

Measure	Time frame
• Gender-questionnaire compiled for the current study • Objective health: cardiovascular disease, metabolic disease, muscular skeletal disease (anamnesis, laboratory analysis of blood, ECG) • Functional parameters, physical activity during daily life, fitness (e.g. gait speed, hand grip strength, RAPA-rapid assessment of physical activity), objective physical activity (accelerometry) • Body composition (DXA) • Nutritional assessment (EPIC) • Cognitive tests (e.g. MMSE)	—

Measure

Time frame

• Gender-questionnaire compiled for the current study • Objective health: cardiovascular disease, metabolic disease, muscular skeletal disease (anamnesis, laboratory analysis of blood, ECG) • Functional parameters, physical activity during daily life, fitness (e.g. gait speed, hand grip strength, RAPA-rapid assessment of physical activity), objective physical activity (accelerometry) • Body composition (DXA) • Nutritional assessment (EPIC) • Cognitive tests (e.g. MMSE)

—

Secondary

Measure	Time frame
• Subjective health (questionnaire) • Quality of life (questionnaire) • Sex life (questionnaire) • Use of medication in the past three and 12 month • Lifestyle factors (questionnaire assessing smoking, alcohol and drug consumption habits) • ADL/Barthel-Index • Quality of sleep (Pittsburgh sleeping quality index –PSQI)	—

Countries

Germany

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 15, 2026