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Measuring Gait Variability in Multiple Sclerosis (MS): exploring new markers for clinical monitoring

Measuring Gait Variability in Multiple Sclerosis (MS): exploring new markers for clinical monitoring

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00016156
Enrollment
128
Registered
2019-04-15
Start date
2019-08-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Sclerosis G35

Interventions

Group 1: MS patients: Gait variability in MS patients with a range of disability levels is to be examined by means of wireless inertial sensors, with measurement occasions separated by an interval of
Flachenecker et al., 2003), depression (ADS-K
Hautzinger et al., 2012) and body awareness (FMI
Wallach et al., 2006) is administered and patients are asked to report the number of falls that occurred during the past 12 months.

Sponsors

Klinikum Bayreuth GmbH, Klinik für Neurologie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: MS diagnoses based on McDonald criteria; ability to walk for at least six minutes without a walking aid; age range 18-65 years

Exclusion criteria

Exclusion criteria: Able to walk only with walking aid

Design outcomes

Primary

MeasureTime frame
Determine sensitivity of inertial sensors to anomalies in gait variability (e.g. MTC-variability) across MS patients with a varying level of disability (EDSS: 0-6). The primary outcome is reached after the gait variability of all MS patients and healthy controls has been analyzed at one time (July 2020).

Secondary

MeasureTime frame
Determine sufficiency of test-retest reliability of gait variability parameters derived with inertial sensors across a period of 4-6 months.

Countries

Germany

Contacts

Public ContactJuliane Stöhr

Klinikum Bayreuth GmbH, Studienzentrum Klinik für Neurologie, organisatorische Leitung

studienzentrum.neurologie@klinikum-bayreuth.de0921/4003440

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026