Evaluation of short- und long-term morbidity of bowel mobilisation in patients with epithelial ovarian cancer after primary undergoing debulking surgery with special interest on Low anterior resection syndrome (LARS) - a retrospective analysis.

Evaluation of short- und long-term morbidity of bowel mobilisation in patients with epithelial ovarian cancer after primary undergoing debulking surgery with special interest on Low anterior resection syndrome (LARS) - a retrospective analysis. - KEM-GO-2 (LARS)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00016155

Enrollment

400

Registered

2019-07-29

Start date

2019-01-21

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C56 K59

Interventions

Group 1: Evaluation of the LARS score in patients undergoing debulking surgery for ovarian cancer who underwent sigma / rectosigmoid or deep anterior rectal resection. The "control cohort" will be:

2) breast cancer patients (matched-pair) who have neo / adjuvant chemotherapy based on their diagnosis but no history of abdominal/bowel surgery.

Eligibility

Sex/Gender

Female

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Ovarian cancer patients who underwent resection of sigma / rectosigmoid or deep anterior rectal resection during debulking surgery (period 2011-2018) will be recruited in this study. As a "control cohort" (this group will also be interviewed using the LARS questionnaire to record LARS score): 1) Patients who have also been treated for primary ovarian cancer but who did not receive bowel surgery as part of the debulking surgery; 2) breast cancer patients (matched-pair) who had neo / adjuvant chemotherapy based on breast cancer diagnosis, and no history of abdominal surgery .

Exclusion criteria

Exclusion criteria: All patients with diverting ostomy, postoperative anastomotic leak, history of abdominal radiotherapy.

Design outcomes

Primary

Measure	Time frame
The aim of the present study is to evaluate the prevalence of the low anterior resection syndrome (LARS) in patients with advanced epithelial ovarian cancer..	—

Secondary

Measure	Time frame
• Comparison of the prevalence of LARS in patients with ovarian cancer with and without sigma / rectosigmoid or deep anterior rectal resection and breast cancer patients who had no abdominal / intestinal surgery. • Prevalence of minor LARS and major LARS in patients with ovarian cancer after sigma / rectosigmoid or deep anterior rectal resection. * Evaluation of risk factors for LARS	—

Countries

Germany

Contacts

Public ContactBeyhan Ataseven

Abteilung für Gynäkologie und Gynäkologische OnkologieKliniken Essen-Mitte

studiengo@kem-med.de

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026