health promoting potential Healthy volunteers
Conditions
Interventions
Group 1: Nasturtium (BITC-containing), 7 days 1.5 g and further 7 days 3 g, which are taken in the morning and evening at intervals of about 12 h. Special diet during washout (7 days before interventi
Sponsors
Universitätsklinikum FreiburgInstitut für Infektionsprävention und KrankenhaushygieneMolekulare Präventivmedizin
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: healthy, non-smokers
Exclusion criteria
Exclusion criteria: acute and chronic diseases, acute peptic ulcer, acute nephritis, pregnancy, breastfeeding, taking antibiotics (acute, during the last three months), known allergy to Cruciferous vegetables and BMI > 25 or <18.5
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| anti-inflammatory potential of nasturtium, before and after intervention, by PGE2 measurement in the blood and peripheral immune cells, which are isolated from blood with and without stimulation in vitro. | — |
Secondary
| Measure | Time frame |
|---|---|
| Alteration of inflammatory markers in the respiratory air condensate, modification of the composition of the gut microbiota (totality of colonizing microorganisms), release of signaling molecules | — |
Countries
Germany
Contacts
Public ContactCorinna Herz
Universitätsklinikum Freiburg, Institut für Infektionsprävention und KrankenhaushygieneMolekulare Präventivmedizin
Outcome results
None listed