Sleep stage mediated hemodynamic state modulation reflected by spectral variation of photoplethysmographic pulse volume curves

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00016123

Enrollment

Registered

2018-12-17

Start date

2018-12-17

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G47.3

Interventions

Group 1: During diagnostic nighttime polysomnography in patients that are for the first time admitted to the sleep laboratory pulse volume curves (PVC) from the pulse oximeter are recorded. In order t

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: normal electricity of the heart is confirmed and sinus rhythm of the cardiac cycles is observed

Exclusion criteria

Exclusion criteria: - heart diseases and heart insufficiency are excluded - vessel diseases are excluded

Design outcomes

Primary

Measure	Time frame
For each sleep stage for at least 10 samples of 32 seconds recording time the absolute values of signal intensity of each frequency peak of the FFT is determined in the range of 0-10Hz. Due to the fact that these absolute values are varying in dependence on perfusion at the oximeter site they are transformed into relative values. The sum of all amplitude maxima is set to 100% and each frequency peak is assigned by it relative contribution to 100%. For each sleep stage the homogeneity of the results of at least 10 samples is investigated by Bartlett test. When homogeneity within one sleep stage is confirmed the results for the different sleep stages are tested for significant differences (p<0.05) by analysis of variance (ANOVA). Primary outcome is reached when intra individual reproducibility of the results is confirmed that always homogeneity within one sleep stage occurs and the only differences are those in the comparison of sleep stages to each other.	—

Measure

Time frame

For each sleep stage for at least 10 samples of 32 seconds recording time the absolute values of signal intensity of each frequency peak of the FFT is determined in the range of 0-10Hz. Due to the fact that these absolute values are varying in dependence on perfusion at the oximeter site they are transformed into relative values. The sum of all amplitude maxima is set to 100% and each frequency peak is assigned by it relative contribution to 100%. For each sleep stage the homogeneity of the results of at least 10 samples is investigated by Bartlett test. When homogeneity within one sleep stage is confirmed the results for the different sleep stages are tested for significant differences (p<0.05) by analysis of variance (ANOVA). Primary outcome is reached when intra individual reproducibility of the results is confirmed that always homogeneity within one sleep stage occurs and the only differences are those in the comparison of sleep stages to each other.

—

Secondary

Measure	Time frame
The secondary outcome is reached if the observed differences between the results of the different sleep stages are interindividually comparable values by t-test (pairs) or ANOVA (multiple). If these values are different a possible systematic influence by age, gender or body-mass-index is investigated by factorial analysis.	—

Countries

Germany

Contacts

Public ContactJens Kerl

Fachkrankenhaus Kloster Grafschaft GmbH

j.kerl@fkkg.de02972-7911703

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026