G93.80 R40
Conditions
Interventions
Group 1: Light levels <500lux during the day, <10lux during the night. Normal lighting conditions in the patients' rooms.
Group 2: Increased daily light dose, light source mimics the naturally ocurrin
Sponsors
Universität Salzburg, Zentrum für kognitive Neurowissenschaften
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: We will include patients with an apallic syndrome (unresponsive wakefulness syndrome, UWS, persistent vegetative state, PVS), as well as patients in a minimally conscious state (MCS).
Exclusion criteria
Exclusion criteria: The only exclusion criterion are strong vegetative reactions (dysautonomy) and/or motor agitation due to the study protocol, which renders data collection impossible or insensible. The decision regarding the exclusion of a patient is up to the local medical study leader. The local medical study leaders assign the suitable patients to the study following an extensive evaluation of their clinical state, e.g. regarding infections. Information regarding the medication will be collected, but is not defined as an exclusion criterion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Coma Recovery Scale-Revised scores (best score out of two assessments on days 6 and 7 of the protocol), daily variations in body temperature, daily variations in ecg-derived measures | — |
Countries
Austria
Contacts
Public ContactManuel Schabus
Universität Salzburg, Zentrum für kognitive Neurowissenschaften
Outcome results
None listed