Bioavailability of fluoride in saliva after administration of fluoridated bioactive glass.

Bioavailability of fluoride in saliva after administration of fluoridated bioactive glass. - Fluoridated bioactive glass

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00016038

Enrollment

Registered

2018-12-05

Start date

2018-03-05

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Z29

Interventions

Group 1: Test subjects are brushing their teeth with a toothpaste containing 1450 ppm NaF (Eurodont, MAXIM Markenprodukte, Pulheim, Germany). Toothbrushing is carried out according to the Bass method

BIOMIN, London, UK).

Eligibility

Sex/Gender

All

Age

20 Years to 28 Years

Inclusion criteria

Inclusion criteria: Caries free, good oral health, normal saliva secretion

Exclusion criteria

Exclusion criteria: Systemic diseases, periodontitis, other oral diseases

Design outcomes

Primary

Measure	Time frame
Primary endpoint is the comparison of the fluoride concentration in saliva application of NaF, AmF and fluoridated bioactive glas at measuring points T3 and T4. The null hypothesis is that there are no differences between the applied fluoride formulations Secondary endpoint is the comparison of the fluoride concentration within the groups (NaF, MaF and fluoridated bioactive glass) at the measuring points T1, T2, T3 and T4 compared to T0	—

Measure

Time frame

Primary endpoint is the comparison of the fluoride concentration in saliva application of NaF, AmF and fluoridated bioactive glas at measuring points T3 and T4. The null hypothesis is that there are no differences between the applied fluoride formulations Secondary endpoint is the comparison of the fluoride concentration within the groups (NaF, MaF and fluoridated bioactive glass) at the measuring points T1, T2, T3 and T4 compared to T0

—

Secondary

Measure	Time frame
Comparison of the different measuring time points	—

Countries

Germany

Contacts

Public ContactElla Naumova

Universität Witten/Herdecke Professur für biologische und materialkundliche Grundlagen der Zahnmedizin

ella.naumova@uni-wh.de02302926640

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 2, 2026