Identification of genetic variations in patients with aortic type B dissection

Identification of genetic variations in patients with aortic type B dissection - genetics type B dissection

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00015943

Enrollment

250

Registered

2019-09-06

Start date

2018-10-25

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I71.0

Interventions

Group 1: Registration of patients with aortic type B dissection, connective tissue gene investigation

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: Included will be patients over 18 years that are reffered to the department of vascular and endovascular surgery (University Hospital Heidelberg). Aortic type B dissection will be diagnosed with Computer tomography angiography (CT-A) or magnetic resonance angiography (MR-A) independetly to the study protocol. Both complicated, uncomplicated acute and chronic type B dissections will be included into the study. Patients give their written consent for genetic analysis and skin biopsy.

Exclusion criteria

Exclusion criteria: pregnant women, age < 18, traumatic aortic dissection, refusal of patient consent, local anesthetic intolerance (no skin biopsy!)

Design outcomes

Primary

Measure	Time frame
Association of genetical findings with aortic dissection Association of genetical findings with clinical Parameters (disease age of onset, clinical course, follow up)	—

Secondary

Measure	Time frame
phenotypical findings (e.g. from skin biopsy)	—

Countries

Germany

Contacts

Public ContactPhilipp Erhart

Klinik für Gefäßchirurgie und Endovaskuläre Chirurgie, Universitätsklinikum Heidelberg

philipp.erhart@med.uni-heidelberg.de06221 56 6249

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Apr 4, 2026