J44.8 J44.9
Conditions
Interventions
Group 1: The questions of the COSYCONET- 2 study represent a specification and extension of the COSYCONET study. It is planed to recruit 400 patients of GOLD grade 0-2 (mainly GOLD 0 and 1) and additi
Sponsors
Philipps-Universität Marburg
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. male or female, 2. 40 years old and older 3. Diagnosis COPD (GOLD 1 - 4) or 4. smoker or ex smoker with minimal 10 packyears and normal lungfunction (FEV1/FVC > =0.7 after bronchodilatation) and symptoms (>= 10 in CAT questionnaire or >= 2 in mMRC scale) or inhale minimal one bronchodilatator. 5. signed informed consent 6. cognitive and physical ability to meet the demands of the study protocol
Exclusion criteria
Exclusion criteria: Having undergone lung surgery (e.g. lung volumen reduction, lung transplant) Patients with lung cancer under treatment Moderate or severe exacerbation within the last 4 weeks Unable to understand the intention of the project, former member of COSYCONET
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main outcome will be the multidimensional BODE-Score: however in COSYCONET-2 this score lays not in the focus of interest. Instead the aim is to answer many specific questions with specific disease entities and specific markers. | — |
Secondary
| Measure | Time frame |
|---|---|
| - to elaborate if the therapy of extrapulmonal disorders influence the progress of the COPD - to elaborateif the therapy of the COPD influence the progress of extrapulmonal disorders -to elaborate to what extend the comorbidity asthma through the analysis of sputume and exhaled nitirc oxide could be quatified - to elaborate to what extend a new classification system could be developed for patients with light to moderate COPD - to elaborate if patients with severe COPD could be differentiated in variable phenotypes and progression forms which are relvant for the therapy -to describe the knowledge and self-management of COPD patients and to find out if knowledge and way of self-management correlate with the progression of the COPD -to collect actual data of therapy of COPD patients and reasons why this therapy was chosen -to identify markers in the blood with the aim to characterize the correlation between specific and unspecific markers and the COPD - to analyse the utilization of the health care system and the associated costs | — |
Countries
Germany
Contacts
Public ContactSandra Söhler
Philipps-Universität Marburg Klinik für Innere Medizin mit Schwerpunkt Pneumologie Geschäftsstelle Kompetenznetz Asthma/COPD
Outcome results
None listed