G97.0
Conditions
Interventions
Group 1: Retrospective collection of prevalence of post- puncture disorders in all patients, who had a lumbal puncture in the period of 02/16 – 02/18 at the Department of Neuropediatrics and Muscle Di
Sponsors
Universitätsklinikum Freiburg
Eligibility
Sex/Gender
All
Age
4 Years to 25 Years
Inclusion criteria
Inclusion criteria: - Age between 4 and 25 years at the time of the lumbar puncture - lumbar puncture performed between February 2016 and February 2018 at the "Zentrum für Kinder- und Jugendmedizin Freiburg"
Exclusion criteria
Exclusion criteria: - oncological diagnosis at the time of lumbar puncture - clouding of consciousness at the time of lumbar puncture or in the following 72h
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - assessment of the prevalence of PDPH (as defined by IHS) within 72h after lumbar puncture - case number calculation for subsequent planned multicenter AMG (German medicinal products act) study | — |
Secondary
| Measure | Time frame |
|---|---|
| - recording the occurrence of additional symptoms (nausea, vomiting, impaired vision) - recording the onset and duration of symptoms - determination of the intensity of pain on VAS scale (as far as recallable) - determination of the necessity of hospitalization (incl. length of stay) - determination of the necessity of an epidural blood patch - subgroup analysis of patients with spinal muscular atrophy (SMA) type I, II and III who undergo regular therapeutic lumbar punctures for intrathecal Nusinersen (©Spinraza) and comparison with normal pediatric cohort | — |
Countries
Germany
Contacts
Public ContactDavid Schorling
Zentrum für Kinder- und Jugendmedizin - Klinik für Neuropädiatrie und Muskelerkrankungen.
Outcome results
None listed