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Reduction of the red cell concentrate use by patient blood management. Changing the pretransfusional hemoglobin trigger by education of transfusion triggers and modification of the transfusion ordering form

Reduction of the red cell concentrate use by patient blood management. Changing the pretransfusional hemoglobin trigger by education of transfusion triggers and modification of the transfusion ordering form

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00015857
Enrollment
20000
Registered
2018-11-08
Start date
2015-07-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

D62 D63

Interventions

Group 1: Four study periods were defined (Fig. S1). The first evaluation period (I), July to September 2014, was used as baseline comparator. no education of physicians (historical cohort) Group 2: F

Sponsors

Universitätsklinikum Greifswald
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: All patients of the following departments were enrolled: surgical departments (general, trauma, orthopedics, neurosurgery, urology, gynecology and obstetrics, surgical intensive care) and medical departments (gastroenterology, pulmonology, nephrology, cardiology, hemato-oncology, medical intensive care).

Exclusion criteria

Exclusion criteria: red blood cell exchange transfusion; missing Hb value within 24h before transfusion

Design outcomes

Primary

MeasureTime frame
The primary endpoint was the change of median pretransfusional Hb-values between evaluation periods.

Secondary

MeasureTime frame
Secondary endpoints were changes in the absolute number of transfused red blood cell concentrates in relation to the number of treated patients, and changes in numbers of red blood cell concentrate-transfusions with a pretransfusional Hb-value of the patient of >10 g/dl. Safety endpoints were the rate of documented in-hospital acute coronary syndrome, all-cause in-hospital mortality, and the length of in-hospital stay.

Countries

Germany

Contacts

Public ContactAndreas Greinacher

Abteilung TransfusionsmedizinUniversitätsmedizin Greifswald

greinach@uni-greifswald.de03834 865482

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026