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Evaluation and correlation of Nociception Level Index (NOL) and Surgical Pleth Index (SPI) for assesment of postoperative pain and opioid demand during recovery room stay

Evaluation and correlation of Nociception Level Index (NOL) and Surgical Pleth Index (SPI) for assesment of postoperative pain and opioid demand during recovery room stay

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00015844
Enrollment
200
Registered
2020-06-12
Start date
2020-07-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative pain

Interventions

Group 1: The SPI or NOL value is recorded at the end of the surgery. The correlation of the NOL/SPI value with the occurance of postsurgical pain is then analyzed.

Sponsors

Universitätsklinikum Schleswig-Holstein
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with elective planned surgery in balanced general anesthesia (intubation anesthesia or laryngeal mask) using sevoflurane and sufentanil or in total intravenous anesthesia (TIVA) using propofol and sufentanil.

Exclusion criteria

Exclusion criteria: - Age under 18 years - Postoperative monitoring in the intensive care unit - atrial fibrillation - AV block> 1 degree - pacemaker - severe peripheral neuropathy - pregnancy - lack of consent - legal support

Design outcomes

Primary

MeasureTime frame
The primary endpoint of this study is the prediction of pain levels and opioid demand in the recovery room based on the measurement results of the NOL monitor intraoperative.

Secondary

MeasureTime frame
1. Correlates the NOL with the SPI at the end of the surgery (wound closure) 2. Correlates the NOL at the end of the surgery (wound closure) with hemodynamic parameters such as heart rate and blood pressure. 3. Are there age-specific differences when estimating the postoperative pain level using the NOL / SPI. 4. Are there gender differences when estimating postoperative pain levels using the NOL / SPI. 5. Are there differences between the assessment of postoperative pain using NOL / SPI under balanced anesthesia (sevoflurane + opioid) and totally intravenous anesthesia (propofol + opioid)

Countries

Germany

Contacts

Public ContactLars Hummitzsch

Klinik für Anästhesiologie und operative Intensivmedizin, Universtitätsklinikum Schleswig Holstein, Campus Kiel

Lars.Hummitzsch@uksh.de043150020801

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026