prostate cancer, mamma carcinoma, colorectal carcinoma H40.1
Conditions
Interventions
Group 1: Patients with prostate cancer and planned radical prostatectomy
Contact-free examinations:
x. Determination of refraction and visual acuity
xi. Slit lamp finding (phak / pseudophak), anomali
Sponsors
Diakonie Klinikum Dietrich Bonhoeffer GmbH
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: For the test group with prostate cancer 1. Patients with prostate cancer (all stages) on whom a radical prostatectomy is planned in Neubrandenburg 2. Willingness of patients to participate in the study with an informed written consent For the comparison group 1. Patient of the eye clinic, male sex 2. no history of prostate cancer known 3. PSA value =4.5 ng / ml 4.Willingness of patients to participate in the study with written consent For the test group with breast cancer 1. Patients with breast cancer (all stages) 2. Willingness of patients to participate in the study with written consent For the test group with colorectal cancer 1. Patients with colorectal cancer (all stages) 2. Willingness of patients to participate in the study with written consent
Exclusion criteria
Exclusion criteria: For all test groups 1. Glaucoma (anamnesis and HRT examination) 2. Other eye disease that interferes with an IOP measurement or examination of the anterior segment of the eye 3. Malignant disease other than prostate cancer, breast cancer and colon cancer (currently or within the last 15 years) 4. Rheumatologic or autoimmune disease 5. Allergy to eye drops with local anesthetics, fluorescein and preservatives For the comparison group 1. Glaucoma (anamnesis and HRT examination) 2. Other eye disease that interferes with IOP measurement or examination of the anterior segment of the eye 3. Malignant disease (current or within the last 15 years) 4. Rheumatologic or autoimmune disease 5. history of prostate cancer 6. increased PSA value 7. Allergy to eye drops with local anesthetics, fluorescein and preservatives
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Does the intraocular pressure differ between patients with prostate cancer and a healthy comparison group? Does the intraocular pressure in prostate cancer, breast cancer or colorectal cancer patients change after surgical tumor removal compared to preoperative values? Is there a difference in systemic levels of potential chemical mediator between prostate cancer patients and a healthy comparison group? Do the absolute values and their postoperative change correlate with the intraocular pressure? After completing the recruitment, the data of all four patient groups are evaluated with the program STATISTICA (StatSoft). | — |
Secondary
| Measure | Time frame |
|---|---|
| Does the intraocular pressure or the postoperative pressure change correlate with pre-, intra- or postoperative data of patients with prostate cancer, breast cancer or colorectal cancer (including histological findings and tumor staging)? After completing the recruitment, the data of all four patient groups are evaluated with the program STATISTICA (StatSoft). | — |
Countries
Germany
Contacts
Public ContactUlrike Holland
Diakonie Klinikum Dietrich Bonhoeffer GmbH
Outcome results
None listed