Prospective Comparison of four antimicrobial susceptibility testing methods ( Biomerieux VITEK 2, Liofilchem MIC Test Strips, Merlin MICRONAUT MIC-Strip, Bio Rad Susceptibility Disks ) to determine in vitro activitiy of Piperacillin/Tazobactam against Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa in blood culture isolates

Prospective Comparison of four antimicrobial susceptibility testing methods ( Biomerieux VITEK 2, Liofilchem MIC Test Strips, Merlin MICRONAUT MIC-Strip, Bio Rad Susceptibility Disks ) to determine in vitro activitiy of Piperacillin/Tazobactam against Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa in blood culture isolates - BK Tazo

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00015813

Enrollment

150

Registered

2018-11-15

Start date

2018-10-26

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

A41.51 A41.52 A41.58

Interventions

Group 1: Measurement of the minimum inhibitory concentration (MIC) for piperacillin / tazobactam with Biomerieux VITEK 2 AST 248 Group 2: Measurement of the minimum inhibitory concentration (MIC) for

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Blood cultures isolates with Escheria coli, Klebsiella pneumonia and Pseudomonas aeruginosa found at the University Hospital Bonn from 2016 to 2018.

Exclusion criteria

Exclusion criteria: From each patient only one isolate is included.

Design outcomes

Primary

Measure	Time frame
Categorical agreement between each of the methods for Piperacillin/Tazobactam based on EUCAST	—

Secondary

Measure	Time frame
Categorical agreement between each of the methods for Piperacillin/Tazobactam based on CLSI. Comparison of the minimum inhibitory concentration	—

Countries

Germany

Contacts

Public ContactThomas Gehring

Institut für Medizinische Mikrobiologie, Immunologie und Parasitologie

thomas.gehring@ukbonn.de022828715952

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026