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Prospective, randomized, monocentric study for the determination of device-related dead spaces under controlled ventilation under general anesthesia

Prospective, randomized, monocentric study for the determination of device-related dead spaces under controlled ventilation under general anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00015797
Enrollment
34
Registered
2018-10-25
Start date
2018-11-28
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spine operations in prone position

Interventions

Sponsors

St. Josef- und St. Elisabeth- Hospital gGmbH Klinik für Anästhesiologie und operative Intensivmedizin
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - All patients who would like to receive general anaesthesia for orthopaedic surgery at the Catholic Hospital Bochum - ASA 1-3 ASA The Classification of the American Society of Anesthesiologists (ASA Classification I- IV) is a widely applied categorization of the preoperative status of patients. It has a good predictive value regarding perioperative morbidity and mortality.

Exclusion criteria

Exclusion criteria: - lack of clarification or consent - pregnancy - simultaneous participation in another study - ASA IV or higher - COPD with a pathological image CO2 >50mmHg or a base excess of >8 or a respiratory acidosis pH < 7.35 - intolerance to sevoflurane (e.g. malignant hyperthermia or muscle disease), remifentanil or piritramide

Design outcomes

Primary

MeasureTime frame
- end expiratory CO2 (et CO2) - respiratory minute volume (AMV)

Secondary

MeasureTime frame
- total dead volume (Vds in ml) - alveolar ventilation (VTalv) = Vds minus the aparative dead space percentage, - Dead space quotients = dead space volume / exhaled breath volume (Vds/VTE) - breathing rate (AF), ventilation pressures, lung compliance, resistance, breathing work (WOB)

Countries

Germany

Contacts

Public ContactMartin Bellgardt

St. Josef- und St. Elisabeth- Hospital gGmbH Klinik für Anästhesiologie und operative Intensivmedizin

m.bellgardt@klinikum-bochum.de+492345096700

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026