Metabolic health and immune status in young obese subjects

Metabolic health and immune status in young obese subjects - MeGA

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00015784

Enrollment

400

Registered

2018-11-23

Start date

2018-11-20

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

E66 E11

Interventions

Group 1: Adult, overweight (Body mass index > 30 kg/m²) with or without influenca vaccination Group 2: Healthy adult normal weight individuals (BMI: 20-24.99 kg/m²) with or without influenca vaccinati

Eligibility

Sex/Gender

All

Age

25 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age: 25-65 years Exposure: Normal weight (BMI: 20-24.99 kg/m²) and overweight/adipose (BMI: >30kg/m²)

Exclusion criteria

Exclusion criteria: - Antibiotics or corticosteroids use 3 months prior to the baseline visit - Current use of immunosuppressive medicine - History of significant illness - Acute febrile illness

Design outcomes

Primary

Measure	Time frame
B-lymphocytes (FACS)	—

Secondary

Measure	Time frame
Oral glucose tolerance test. Immunophenotyping of T-cell subpopulations (CD4+, CD8+, NK cells, Tregs, memory T cells), Inflammation markers: Plasma levels of interleukins, IFN-gamma, CCL5, TNF-alpha	—

Countries

Germany

Contacts

Public ContactChristine Meisinger

Lehrstuhl für Epidemiologie, Universität Augsburg

christine.meisinger@med.uni-augsburg.de+49 821 598 6471

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 9, 2026