Comparison of the work-of-breathing and the activity of the muscles of breathing through Surface-electromyography during invasive lung Ventilation

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00015780

Enrollment

Registered

2018-10-23

Start date

2018-10-23

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

J44 J84

Interventions

Group 1: Measuring of sEMG (Surface-electromyography) and pressure (gastral and esophageal) in the fully awake an spontaneous breathing state and in the sedated and assisted spontaneous breathing stat

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Indication for elective bronchoscopy: - COPD GOLD II-III (chronic obstructive pulmonary disease) - Interstitial lung disease (confirmed or suspected) - Age > 18 years

Exclusion criteria

Exclusion criteria: - indication for acute bronchoscopy (i.e. hemoptysis, tumor-recanalisation) - neuromuscular diseases - drug abuse - anamnestic esphageal Stenosis or varices - risk for bleeding in the laborchemistry - pregnancy

Design outcomes

Primary

Measure	Time frame
The Primary Goal is to identify changes in the work of brathing and the sEMG-signal (Surface-electromyography) during invasive ventilatkion. For aquiring these information we continously monitor the sEMG of the diaphragm and the intercostal muscles via small electrodes glued to the Skin as well as the esophageal pressure via a esophageal probe. During assisted Ventilation the data provided by the lung Ventilator (mouth pressure, gas-flow, FiO2, FeCO2) were also documented.	—

Measure

Time frame

The Primary Goal is to identify changes in the work of brathing and the sEMG-signal (Surface-electromyography) during invasive ventilatkion. For aquiring these information we continously monitor the sEMG of the diaphragm and the intercostal muscles via small electrodes glued to the Skin as well as the esophageal pressure via a esophageal probe. During assisted Ventilation the data provided by the lung Ventilator (mouth pressure, gas-flow, FiO2, FeCO2) were also documented.

—

Secondary

Measure	Time frame
Another Point of interest were the changes in the sEMG-signal provoked by movements (cough, active and passive movements of the extremities).	—

Countries

Germany

Contacts

Public ContactMax Kustermann

Klinikum Konstanz II. Medizin

max.kustermann@glkn.de075318011448

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026