Muscular atrophy, bone resorption,Deconditioning of the cardiovascular system, impairment of the vestibular system, impairment of cognitive performance, fluid shifts, eye changes, SANS
Conditions
Interventions
Group 1: Intervention Group 1: 6° HDBR with supine centrifugation at +1Gz at the center of mass for 30 minutes continuous per day.
Group 2: Intervention group 2: 6° HDBR with supine centrifugation at
Sponsors
DLR - Institut für Luft- und Raumfahrtmedizin
Eligibility
Sex/Gender
All
Age
24 Years to 55 Years
Inclusion criteria
Inclusion criteria: Physically and mentally healthy test subjects that are able and declare their willingness to participate in the entire study and successfully passed the psychological and medical screening - Aged between 24 and 55 years old with a Body Mass Index (BMI) of 19 - 30 kg/m2, height between 153 -190 cm - Non-smoker, for at least six months before the start of the study - Capable of completing the study - Willing to stay in bed with or without weight-bearing (artificial gravity) for 60 days - Demonstrable medical insurance and official certificate of absence of criminal record - Demonstrable dentist certificate
Exclusion criteria
Exclusion criteria: - Drug, medication or alcohol abuse (regular consumption of more than 20-30 g alcohol/day)* - A requirement for any prescription medications - Vegetarian, vegan (during the study) - Migraine, chronic headache - Insomnia or other sleep disorders - Previous psychiatric illness - Claustrophobia - Increased intraocular pressure - Any eye disorder that could significantly impact or jeopardize visual function - Hyperopia > +5.0 Diopters - Myopia > - 6 Diopters - Astigmatism > 3 Diopters - History of laser surgery, glaucoma and retinal surgery - Hiatus hernia - Gastro-oesophageal reflux - Gastrointestinal stenosis, dysphagia - Current or history of chronic bowel disease - Diabetes mellitus - Rheumatic illness - Current or a history of (chronic) pulmonary disease - Current muscle or joint disease or disorder - History of prolapsed intervertebral disc - Chronic back complaints - Bone fractures less than 1 year prior to study - Kidney disorder: deviations from normal values for creatinine in plasma. Deviations from normal values (Normal values for creatinine in plasma 30 dB, or implanted hearing device - Known Chiari-malformation - History of fracture(s) at proximal femur (hip area), less than 2 years, and/or with remainin
Design outcomes
Primary
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Secondary
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Countries
Germany
Contacts
Public ContactAndrea Nitsche
DLR - Institut für Luft- und Raumfahrtmedizin
Outcome results
None listed