K90.8 M05 M45 L40.5 M12.3
Conditions
Interventions
Group 1: Rheumatic symptoms recorded 1) by patients with Whipple's disease on specific questionnaires are to be compared with 2) the response of patients with rheumatoid arthritis, psoriatic arthropat
Sponsors
DRK Krankenhaus Neuwied
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Diagnostic criteria:; Whipple’s disease, [S2k Leitlinie Morbus Whipple, Z. Gastroenterol 2015;53:418] those with rheumatoid arthritis the 2010 American College of Rheumatology (ACR) and European League Against Rheumatism classification criteria, those with psoriasis arthritis – the CASPAR criteria, and the patients with axial spondyloarthritis – the ASAS classification criteria, Palindromic arthritis was diagnosed when episodic and saltatory arthritis with articular pain and swelling occurred in patients in the presence of either anti-citrullinated protein antibodies (ACPA) in 14 patients or isolated positive rheumatoid factor in one patient.
Exclusion criteria
Exclusion criteria: when no consent is given by the patient
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All patients consenting and fulfilling the diagnostic criteria are asked to answer questionnaires as there were 40 patients with Whipple's disease, +20 patients with Whipple's disease as validation group + 30 patients with rheumatoid arthritis +25 patients with axial spondyloarthritis+ 21 patients with psoriatic arthritis + 15 patients with palindromic arthritis. Primary outcome measure is registration and evaluation of the clinical symptoms recorded in the questionnaires. | — |
Secondary
| Measure | Time frame |
|---|---|
| The questionnaire results studied with logistic regression analysis to check for clinical usefulness in the differential diagnosis were validated in an additional group of 20 patients with Whipple's disease | — |
Countries
Germany
Contacts
Public ContactVerena Moos
Charité Universitätsmedizin Berlin, Campus Benjamin Franklin Medizinische Klinik 1
Outcome results
None listed