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Perioperatively-Acquired Weakness

Perioperatively-Acquired Weakness - POAW

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00015637
Enrollment
100
Registered
2018-12-10
Start date
2018-11-27
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

M62.5

Interventions

Group 1: Patients with elective surgery without tumor disease without significant comorbidities. Group 2: Patients undergoing anesthesia without surgery (e.g., MRI or CT diagnosis under general anesth

Sponsors

Charité Campus Virchow-Klinikum
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Patients undergoing elective surgery at the Charité - Patients undergoing elective diagnostics in General anaesthesia at the Charité - written consent of the patient

Exclusion criteria

Exclusion criteria: - Age <18 years - Participation in another study - neuromuscular disease - lack of consent of the patient - pregnancy

Design outcomes

Primary

MeasureTime frame
Loss of muscle strength on the first postoperative day measured by hand grip strength (hand grip strength measured by dynamometry on both sides)

Secondary

MeasureTime frame
- Questionnaire on Physical Independence (Functional Independence Measure) - Clinical muscle strenght measurement (MRC score) - lung function tests - Ultrasound examination of the musculature - 6-minute walking test - indirect calorimetry

Countries

Germany

Contacts

Public ContactTobias Wollersheim

Charité - Universitätsmedizin BerlinKlinik für Anästhesiologie m.S. operative Intensivmedizin

tobias.wollersheim@charite.de030450651808

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026