Healthy athletes and non-athletes
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Endurance-trained athletes: national and regional high performance athletes, VO2max > 60ml/kg/min, several years of running experience and participation in national and international competitions. Strength-trained athletes: national and regional high performance athletes, several years of strength training experience or participation in national or international competitions. Sedentary controls: no regular training activities (< 2x/wk physically active, e.g. driving short distances with a bike, garden works, recreational swimming).
Exclusion criteria
Exclusion criteria: - minority - incapacity to consent - diseases (abnormalities) of the musculoskeletal system such as osteoarthritis, spondylarthrosis, joint or spinal deformity - cardiovascular diseases (e.g. hypertension, coronary heart disease, haemodynamically relevant valve viability, severe cardiac arrhythmia) - any acute or chronic disease (e.g. infectious diseases) - disturbance of coagulation activity - anamnestic information on muscle disease - regular medication, in particular non-steroidal anti-inflammatory drugs - intake of food supplements, in particular creatine, carbohydrate, ß-alanine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes of the metabolic profile, which will be explained by the concentration and composition or change of the metabolites. Effects between the groups (i) endurance- and strength-trained athletes, as well as between the two groups of athletes and the sedentarycontrols will be investigates as well as (ii) acute exercise-induced effects and longitudinal changes over the training year (= between timepoint 1, timepoint 2 and timepoint 3). Measurements: Detection of metabolites using GC/MS in venous and capillary blood samples at rest and after a specific exercise test (treadmill test and threshold test or strength test) at three time points in the course of a training year. | — |
Secondary
| Measure | Time frame |
|---|---|
| no secondary outcome | — |
Countries
Germany
Contacts
Universitätsklinikum Heidelberg, Innere Medizin VII: Sportmedizin